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Limited Research

Prostamax

Synthetic Tetrapeptide | Prostate Bioregulator

Prostamax (Lys-Glu-Asp-Pro/KEDP) is a synthetic tetrapeptide bioregulator from the Khavinson peptide family that demonstrates prostate-specific tissue effects. Preclinical research shows anti-inflammatory and tissue-protective properties in chronic prostatitis models, with emerging interest in epigenetic chromatin regulation and anti-aging applications. Human clinical trial data remains limited.

Daily dose

0.5-1mg

Frequency

Once daily

Cycle length

10-20 days

Storage

2-8°C

Key benefits

Prostate tissue regulation, anti-inflammatory effects, chromatin decondensation, cellular aging modulation

How it works

Tissue-specific bioregulator that influences gene expression through heterochromatin decondensation in prostate cells and lymphocytes, potentially reactivating age-suppressed genes

Dosage protocols

Goal

Prostate Health Support

Dose

0.5-1mg daily · Once daily

Route

Subcutaneous injection

Goal

Anti-Aging Protocol

Dose

0.75mg daily · Once daily for 10-20 days

Route

Subcutaneous or oral

Goal

Oral Protocol

Dose

0.5-1mg daily · Once daily on empty stomach

Route

Oral capsule

Research indications

prostate Health

Chronic Prostatitis ManagementPreclinical studies demonstrate reduced inflammation (swelling, hyperemia, lymphoid infiltration) and prevention of sclerotic/atrophic processes in chronic aseptic prostatitis models
Tissue RegenerationEnhanced proliferative and metabolic activity in prostate epithelial cells and fibroblasts, maintaining efficacy in aged tissue samples
Superior to Conventional AgentsPreclinical efficacy surpassed Serenoa repens extract and animal prostate-derived medications in comparative studies

anti Aging

Chromatin DecondensationInduces deheterochromatinization in human lymphocytes, potentially reactivating genes suppressed during aging through pericentromeric chromatin relaxation
Epigenetic ModulationAffects ribosome gene activation and chromosomal structural patterns (chromosomes 1, 9, 16) in elderly subjects aged 75-88 years
Cellular Aging ResearchPart of the Khavinson peptide family studied for geroprotective effects, with long-term Russian clinical protocols showing benefits in elderly populations

immune

Lymphocyte Function OptimizationStudies show effects on lymphocyte chromatin organization, potentially improving immune cell function through gene expression modulation
Nucleolus Organizer ActivationHeightened Ag-positive nucleolus organizer regions observed, suggesting enhanced ribosomal gene activity

Administration

injectable
oral

Interactions

Compatible
EpitalonBoth are Khavinson bioregulators with complementary mechanisms. Prostamax targets prostate tissue while Epitalon focuses on telomerase activation. Russian protocols combine multiple bioregulators for comprehensive anti-aging support.
Compatible
ThymalinSafe combination supporting prostate-immune axis. Both are short Khavinson peptides with different tissue specificities. Long-term Russian studies show safety of multi-peptide bioregulator protocols.
Compatible
PinealonDifferent target tissues with no known interactions. Pinealon targets neurological pathways while Prostamax focuses on prostate tissue. Can be used in comprehensive bioregulator protocols.
Compatible
BPC-157Different mechanisms with no documented interactions. BPC-157 focuses on tissue repair and GI protection while Prostamax provides prostate-specific bioregulation.
Use Caution
5-Alpha Reductase InhibitorsBoth affect prostate tissue - effects may overlap or be amplified. Monitor for enhanced effects and consult healthcare provider if using together.
Monitor Combination
Testosterone/TRTBoth influence prostate tissue. Theoretical concern for combined effects on prostate growth. Monitor PSA levels and prostate symptoms if using together.
Compatible
Saw Palmetto (Serenoa repens)Preclinical studies compared Prostamax favorably to Serenoa repens extract. Different mechanisms - may provide complementary prostate support.

Safety notes

Human clinical trial data not yet published - all dosing extrapolated from preclinical models

Possible side effects include mild injection site reactions, occasional digestive discomfort, and rare headache

Contraindicated when active prostate cancer exists - theoretical concern for stimulating tumor growth

Not recommended during pregnancy, lactation, or in women generally (prostate-specific)

Quality sourcing critical - poor manufacturing can result in contamination causing adverse reactions

Consult healthcare provider before use, especially if taking prostate medications or androgen therapy

Research studies

Benign Prostatic Hyperplasia Model (2014)

Animal model | BPH parameters | Histological assessment

Study examining tetrapeptide Lys-Glu-Asp-Pro effects in benign prostatic hyperplasia model, showing favorable effects on prostate weight and histological parameters.

View study →

Chronic Aseptic Prostatitis - Rat Model (2013)

Rat model | 20 μg/kg IM daily | 45 days observation | Anti-inflammatory effects

Experimental study demonstrating Prostamax reduces inflammation markers (swelling, hyperemia, lymphoid infiltration), prevents sclerotic and atrophic processes, and enhances sexual activity. Efficacy surpassed Serenoa repens and animal prostate extracts.

View study →

Deheterochromatinization in Aging (2012)

Human cell cultures | Elderly subjects | Chromatin relaxation

Georgian Medical News study confirming Prostamax (KEDP) induces deheterochromatinization in chromatin from elderly subjects, potentially reversing age-related gene silencing.

View study →

Lymphocyte Chromatin in Elderly Subjects (2004)

Human lymphocytes | Subjects aged 75-88 | Chromatin structure analysis

Khavinson study showing Prostamax induces ribosome gene activation, chromatin decondensation, and affects structural patterns in chromosomes 1, 9, and 16 in elderly subjects.

View study →

Heterochromatin Effects - Biofizika Study (2004)

Human lymphocyte culture | In situ analysis | Epigenetic effects

Russian study by Meskhi et al. demonstrating Prostamax influences heterochromatin structure in human lymphocytes, with implications for age-related gene expression changes.

View study →